abstract：:Porous scaffolds composed of alginate (AG) and chitosan (CS) were fabricated by combining the formation of polyelectrolyte complex (PEC) with freeze-drying. The AG scaffold was used as a framework with uniformly distributed and interconnected pore structure. The chitosan or chitosan/hydroxyapatite (CS/HA) composite so...

journal_title：International journal of biological macromolecules

authors： Han J,Zhou Z,Yin R,Yang D,Nie J

更新日期：2010-03-01 00:00:00

abstract：:Lacquer polysaccharide (LP) from the sap of the lac tree (Rhus vernicifera) was degraded by hydrochloric acid. The molecular weights (M(w)) of hydrolysis products of lacquer polysaccharide (LPD) decreased with the increase of the reaction temperature. Sulfated derivatives (LPDSs) of LPDs were prepared by the reaction ...

journal_title：International journal of biological macromolecules

authors： Zou C,Du Y,Li Y,Yang J,Zhang L

更新日期：2010-03-01 00:00:00

abstract：:A novel oligomeric SGNH-arylesterase (Sm23) from Sinorhizobium meliloti 1021 was characterized using biochemical and biophysical methods. A sequence comparison of Sm23 with other SGNH members confirmed the presence of catalytic triad (Ser(10), Asp(187), and His(190)) and oxyanion holes (Ser(10)-Gly(50)-Asn(90)). The w...

journal_title：International journal of biological macromolecules

authors： Hwang H,Kim S,Yoon S,Ryu Y,Lee SY,Kim TD

更新日期：2010-03-01 00:00:00

abstract：:Decompaction of DNA-CTA self-assembled complexes by 2-hydroxypropyl-beta-cyclodextrin (2-HP-beta-CD) was studied and the results were compared with beta-CD. Different degrees of 2-HP substitution (0.6, 0.8 and 1.0, respectively) were used and the decompaction was successful with all degrees of substitution. Fluorescen...

journal_title：International journal of biological macromolecules

authors： Carlstedt J,González-Pérez A,Alatorre-Meda M,Dias RS,Lindman B

更新日期：2010-03-01 00:00:00

abstract：:Histones are DNA protective proteins and may adopt different structures under nitrosative stress. Peroxynitrite is a powerful oxidant and nitrating agent and has in vivo existence. In this communication, we report effect of peroxynitrite-mediated oxidation and nitration on the structure of calf thymus H3 histone. Fine...

journal_title：International journal of biological macromolecules

authors： Dixit K,Khan MA,Sharma YD,Moinuddin,Alam K

更新日期：2010-01-01 00:00:00

abstract：:To study the properties and structure of aquatic silk, nest-spinning hydropsychid caddisfly (Stenopsyche marmorata) larva were collected from a Japanese river and the silk glands were removed from the larva by dissecting and dried on the glass plate at room temperature. The silk fibers were obtained by removing fibrou...

journal_title：International journal of biological macromolecules

authors： Tsukada M,Khan MM,Inoue E,Kimura G,Hun JY,Mishima M,Hirabayashi K

更新日期：2010-01-01 00:00:00

abstract：:Liposomes, which release their contents in response to the concentration of glucose, were prepared by modifying the liposomal surface with the conjugate of poly(N-isopropylacrylamide-co-methacrylic acid-co-octadecylacrylate) (P(NIPAM-co-MAA-co-ODA)) and glucose oxidase (GOD). The maximum enzymatic activity of copolyme...

journal_title：International journal of biological macromolecules

authors： Jo SM,Lee HY,Kim JC

更新日期：2009-11-01 00:00:00

abstract：:A novel biopolymer-based superporous hydrogel (SPH) was synthesized through chemical crosslinking by graft copolymerization of 2-hydroxyethyl methacrylate (HEMA) and acrylic acid (AA) on to xanthan gum (XG) via redox initiator system of ammonium persulfate (APS) and N, N, N', N'-tetramethylethylenediamine (TMED), in t...

journal_title：International journal of biological macromolecules

authors： Gils PS,Ray D,Sahoo PK

更新日期：2009-11-01 00:00:00

abstract：:In the present study the effect of iodine on the structural characteristics (by infrared spectroscopy and X-ray) of films made from kidney bean starch was evaluated. The pasting properties as affected by iodine and glycerol were also evaluated. Kidney bean starch showed C-type (mixture of A- and B-type) crystalline st...

journal_title：International journal of biological macromolecules

authors： Singh N,Belton PS,Georget DM

更新日期：2009-08-01 00:00:00

abstract：:Three polysaccharide fractions (DDP1-1, DDP2-1 and DDP3-1) were successfully purified from the crude polysaccharide of Dendrobium denneanum by DEAE-Cellulose and Sephadex G-200 column chromatography. The average molecular weights (Mws) of these fractions were 51.5, 26.1 and 6.95 kDa, respectively. Monosaccharide compo...

journal_title：International journal of biological macromolecules

authors： Fan Y,He X,Zhou S,Luo A,He T,Chun Z

更新日期：2009-08-01 00:00:00

abstract：:Poly(hydroxyethyl methacrylate) (PHEMA) nanoparticles with an average size of 300 nm in diameter and with a polydispersity index of 1.156 were produced by surfactant free emulsion polymerization. Specific surface area of the PHEMA nanoparticles was found to be 996 m(2)/g. Metal-chelating ligand 3-(2-imidazoline-1-yl)p...

journal_title：International journal of biological macromolecules

authors： Karakoc V,Yilmaz E,Türkmen D,Oztürk N,Akgöl S,Denizli A

更新日期：2009-08-01 00:00:00

abstract：:Halymenia durvillei is a red seaweed with a great potential as sulphated galactan producer collected in the coastal waters of small island of Madagascar (Nosy-be in Indian Ocean). To elucidate the structure of its polysaccharide, NMR (1H and 13C), FTIR, HPAEC and different colorimetric methods were carried out. It has...

journal_title：International journal of biological macromolecules

authors： Fenoradosoa TA,Delattre C,Laroche C,Wadouachi A,Dulong V,Picton L,Andriamadio P,Michaud P

更新日期：2009-08-01 00:00:00

abstract：:The purpose of this study was to investigate the immune and antioxidant activities of Glycyrrhiza glabra polysaccharides (GGP) in rats fed high-fat diet. The experiment was performed on four groups of growing Kunming mice. The results of the experiment showed a statistically significant decrease in serum antioxidant e...

journal_title：International journal of biological macromolecules

authors： Hong YK,Wu HT,Ma T,Liu WJ,He XJ

更新日期：2009-07-01 00:00:00

abstract：:We have studied the inhibitory effect of five polyphenols namely, resveratrol, piceatannol, quercetin, quercetrin, and quercetin-3-beta-D glucoside on Escherichia coli ATP synthase. Recently published X-ray crystal structures of bovine mitochondrial ATP synthase inhibited by resveratrol, piceatannol, and quercetin, su...

journal_title：International journal of biological macromolecules

authors： Dadi PK,Ahmad M,Ahmad Z

更新日期：2009-07-01 00:00:00

abstract：:Six low molecular fucoidan (DFPS) derivatives were synthesized successfully, and their potential antioxidant activities were investigated employing various established in vitro systems. All DFPS derivatives possessed considerable antioxidant activity, and had stronger antioxidant ability than DFPS in certain tests. Th...

journal_title：International journal of biological macromolecules

authors： Wang J,Wang F,Zhang Q,Zhang Z,Shi X,Li P

更新日期：2009-06-01 00:00:00

abstract：:We have investigated the protective effect of polysaccharides from Curcuma kwangsiensis (CKP) against oxidative injury in rats fed high-fat diet. The protective effect of CKP was compared with Lovastatin, a well-known antioxidant. Sixty SD rats were used for the experimental study. Oxidative injury was induced by feed...

journal_title：International journal of biological macromolecules

authors： Xu C,Haiyan Z,Hua Z,Jianhong Z,Pin D

更新日期：2009-03-01 00:00:00

abstract：:Biodegradable polyurethane elastomers with tunable hydrophobicity were synthesized by step-growth polymerization techniques using poly(epsilon-caprolactone) (PCL) and 4,4'-diphenylmethane diisocyanate (MDI). The prepolymer was extended with different mass ratios of chitin and 1,4-butane diol (BDO). The effect of chiti...

journal_title：International journal of biological macromolecules

authors： Zia KM,Barikani M,Zuber M,Bhatti IA,Barmar M

更新日期：2009-03-01 00:00:00

abstract：:It is well accepted that porphyrins related to heme, are effectively able to act as pharmaceutical. For instance, they were found to interfere with the aggregation of beta-amyloid peptide. In present study, the influence of heme concentration on the amyloid-type aggregation of ovalbumin was investigated. We provided e...

journal_title：International journal of biological macromolecules

authors： Khodarahmi R,Soori H,Karimi SA

更新日期：2009-01-01 00:00:00

abstract：:The Notch signaling pathway (NSP) is an important intercellular communication mechanism that regulates embryo development and adult physiological functions. The Hairless (H) protein is a powerful antagonist of the NSP by its interaction with the Suppressor of Hairless (Su[H]) protein, recruiting the corepressors Gro a...

journal_title：International journal of biological macromolecules

authors： Paz-Gómez D,Baizabal-Aguirre VM,Valdez-Alarcón JJ,Cajero-Juárez M,Nagel AC,Preiss A,Maier D,Bravo-Patiño A

更新日期：2008-12-01 00:00:00

abstract：:The interaction between xanthan and selected bivalent cations (Ca2+, Mg2+, Mn2+, Fe2+, Cu2+, Zn2+, Cd2+ and Pb2+) was studied by means of conductometry, viscometry, and nuclear magnetic resonance spectroscopy. Xanthan from Xanthomonas campestris was studied in comparison with dextran from Leuconostoc mesenteroides. Wh...

journal_title：International journal of biological macromolecules

authors： Bergmann D,Furth G,Mayer C

更新日期：2008-10-01 00:00:00

abstract：:Reported here is the overexpression, purification and partial characterization of recombinant coxsakievirus B3 2A protease (CVB3 2Apro) from bacterial cells transformed with a plasmid containing the CVB3 2Apro cDNA sequences. The structural investigation showed that the protein contains mostly beta-strand elements and...

journal_title：International journal of biological macromolecules

authors： Maghsoudi N,Khodagholi F,Sadjadi M,Zeinodini M,Sabbaghian M

更新日期：2008-10-01 00:00:00

abstract：:In order to examine the effect of polysaccharides from morinda officinalis (MOP) on bone quality of osteoporosis rats. The osteoporosis in rats was induced by ovariectomy, and MOP (100 or 300 mg/kg) was orally administrated once daily. The animals were assessed 30 days after the operation for bone mineral density, ser...

journal_title：International journal of biological macromolecules

authors： MengYong Z,CaiJiao W,HuSheng Z,XianWu P,JianMin F

更新日期：2008-10-01 00:00:00

abstract：:The Publisher regrets that this article is an accidental duplication of an article that has already been published in Int. J. Biol. Macromol, doi:10.1016/j.ijbiomac.2008.07.012. The duplicate article has therefore been withdrawn. ...

journal_title：International journal of biological macromolecules

authors： Kennedy JF

更新日期：2008-08-19 00:00:00

abstract：:The structure of aggregates formed by the globular protein beta-lactoglobulin (beta-lg) after heat induced denaturation was studied using light scattering and size exclusion chromatography. The influence of varying the pH above the iso-electric point (pH 5.2) was investigated in the absence of added salt. Stable aggre...

journal_title：International journal of biological macromolecules

authors： Mehalebi S,Nicolai T,Durand D

更新日期：2008-08-15 00:00:00

abstract：:Effects of sodium dodecyl sulfate, dodecyltrimethylammonium bromide, sodium chloride, sodium sulfate, methanol and ethanol, on the structure and activity of adenosine deaminase (ADA) were investigated by UV-Vis, circular dichroism spectrophotometry and molecular dynamics (MDs) studies. Relative activity, experimental ...

journal_title：International journal of biological macromolecules

authors： Ajloo D,Taghizadeh E,Saboury AA,Bazyari E,Mahnam K

更新日期：2008-08-15 00:00:00

abstract：:A novel chitin-graft-polyleucine microsphere with hollow construction was prepared via ring-opening polymerization initiated with chitin based on interfacial protocol. The FT-IR and (1)H NMR analysis demonstrated the conjugation with regulated graft length. The study provided a facile one-step route to obtain microsph...

journal_title：International journal of biological macromolecules

authors： Wang J,Liu C,Chi P

更新日期：2008-06-01 00:00:00

abstract：:Large amounts of DNA-enriched biomaterials, such as salmon milts and shellfish gonads, are discarded as industrial waste around the world. Therefore, the utilizations of DNA with the specific function are important for the biomaterial science and the curce technology. We could convert the discarded DNA to an enzymatic...

journal_title：International journal of biological macromolecules

authors： Yamada M,Amoo M

更新日期：2008-06-01 00:00:00

abstract：:Chitosan a natural based polymer is non-toxic, biocompatible and biodegradable. Chemical modification of chitosan to generate new bifunctional materials and finally would bring new properties depending on the nature of the group introduced. In our present study, we prepared phosphorylated chitosan (P-chitosan) by usin...

journal_title：International journal of biological macromolecules

authors： Jayakumar R,Nagahama H,Furuike T,Tamura H

更新日期：2008-05-01 00:00:00

abstract：:To fabricate a biomimetic nanostructured bicomponent scaffolds, two types of chitin/silk fibroin (SF) nanofibrous scaffolds (blend scaffolds and hybrid scaffolds) were prepared by electrospinning or simultaneous electrospinning of chitin/SF solutions. The chitin/SF bicomponent scaffolds were after-treated with water v...

journal_title：International journal of biological macromolecules

authors： Yoo CR,Yeo IS,Park KE,Park JH,Lee SJ,Park WH,Min BM

更新日期：2008-05-01 00:00:00

abstract：:This is the first report on the identification and partial characterization of phospholipase D (EC 3.1.4.4) from Allium sativum (garlic) bulbs (PLD(GB)). The enzyme shares the phenomenon of interfacial activation with other lipolytic enzymes, i.e. the hydrolytic rate increases when the substrate changes to a more aggr...

journal_title：International journal of biological macromolecules

authors： Khatoon H,Talat S,Younus H

更新日期：2008-05-01 00:00:00

abstract：:Four kinds of astragalus polysaccharides (APSs), APS(t), APS(40), APS(50) and APS(60), were extracted by water decoction and one-step or stepwise ethanol precipitation methods, and modified by chlorosulfonic acid-pyridine method to obtain four sulfated APSs (sAPSs) (sAPS(t), sAPS(40), sAPS(50), sAPS(60)), respectively...

journal_title：International journal of biological macromolecules

authors： Huang X,Wang D,Hu Y,Lu Y,Guo Z,Kong X,Sun J

更新日期：2008-03-01 00:00:00

abstract：:In the present study, lipase was immobilized via glutaraldehyde crosslinking on the polysulfone and polyether sulfone asymmetric membranes. The results indicated that the overall immobilization of lipase is related to the hydrophobicity of the membrane material and thus higher immobilization is achieved for polysulfon...

journal_title：International journal of biological macromolecules

authors： Gupta S,Yogesh,Javiya S,Bhambi M,Pundir CS,Singh K,Bhattacharya A

更新日期：2008-03-01 00:00:00

abstract：:Extracellular laccase produced by Cerrena unicolor was immobilized by adsorption or covalent bonds formation on the cellulose-based carrier Granocel. Immobilization was optimized by changing the anchor groups and the methods of activation/immobilization. On the base of measured activity and stability of immobilized pr...

journal_title：International journal of biological macromolecules

authors： Rekuć A,Kruczkiewicz P,Jastrzembska B,Liesiene J,Peczyńska-Czoch W,Bryjak J

更新日期：2008-03-01 00:00:00

abstract：:alpha2-Macroglobulin (alpha2M) is a 718 kDa homotetrameric proteinase inhibitor which undergoes a large conformational change upon activation. This conformational change can occur either by proteolytic attack on an approximately 40 amino acid stretch, the bait region, which results in the rupture of the four thioester...

journal_title：International journal of biological macromolecules

authors： Kaczowka SJ,Madding LS,Epting KL,Kelly RM,Cianciolo GJ,Pizzo SV

更新日期：2008-01-01 00:00:00

abstract：:The morphological analysis of novel quantum dot-hyaluronic acid (QDot-HA) conjugates was carried out with a transmission electron microscope (TEM). Adipic acid dihydrazide-modified HA (HA-ADH) was synthesized and conjugated to quantum dots (QDots) having carboxyl terminal ligands which were activated with 1-ethyl-3-(3...

journal_title：International journal of biological macromolecules

authors： Kim J,Park K,Hahn SK

更新日期：2008-01-01 00:00:00

abstract：:Naturally occurring polyamines are known to interact with a variety of biomolecules and critically involve in some important physiological processes. They have also been shown to influence protein aggregation in vitro in some cases. The aim of the present study was to investigate how polyamines may influence the struc...

journal_title：International journal of biological macromolecules

authors： Rezaei-Ghaleh N,Ebrahim-Habibi A,Moosavi-Movahedi AA,Nemat-Gorgani M

更新日期：2007-12-01 00:00:00

abstract：:Proteins of halophilic archaea function in high-salt concentrations that inactivate or precipitate homologous proteins from non-halophilic species. Haloadaptation and the mechanism behind the phenomenon are not yet fully understood. In order to obtain useful information, homology modeling studies of dihydrofolate redu...

journal_title：International journal of biological macromolecules

authors： Kastritis PL,Papandreou NC,Hamodrakas SJ

更新日期：2007-10-01 00:00:00

abstract：:A combined DSC - HPAEC-PAD approach, gel permeation chromatography and mild long-term acidic hydrolysis were employed to study the effects of amylopectin chain-length distributional and amylose defects on the assembly structures of amylopectin (crystalline lamellae, amylopectin clusters) in A-type polymorphic starches...

journal_title：International journal of biological macromolecules

authors： Koroteeva DA,Kiseleva VI,Sriroth K,Piyachomkwan K,Bertoft E,Yuryev PV,Yuryev VP

更新日期：2007-10-01 00:00:00

abstract：:In our previous publication we had reported the purification and characterization of Clitoria ternatea agglutinin from its seeds on fetuin CL agarose affinity column, designated CTA [A. Naeem, S. Haque, R.H. Khan. Protein J., 2007]. Since CTA binds beta-d-galactosides, this lectin can be used as valuable tool for glyc...

journal_title：International journal of biological macromolecules

authors： Naeem A,Ahmad E,Khan RH

更新日期：2007-10-01 00:00:00

abstract：:In the present study an attempt is made to elucidate the effects of various cosolvents, such as sorbitol, sucrose, xylose and glycerol, on papain. The stabilizing effects of these cosolvents on the structure and function of papain is determined by the activity measurements, fluorescence spectroscopy and differential s...

journal_title：International journal of biological macromolecules

authors： Sathish HA,Kumar PR,Prakash V

更新日期：2007-10-01 00:00:00